Anoghi, 500 m from sea level, is the highest of all the villages. Established some time during the Middle Ages, Anoghi is one of the oldest villages of the island, its elevation ensuring a refuge from the pirates.

This interesting little village can be accessed by two routes. One being the road direct from Vathy, turning at Agros and passing Kathara and the other by the Stavros road. Both trips offer an attractive scenic view, the Stavros route allowing an excellent view of the nearly all the villages of Northern Ithaca whilst the Agros route, winding as it does, round a mountainous area, shows specatular rocks, olive trees and several vineyards.

The Church of Panayia was first built in the Byzantine years, interesting frescoes were added over different time periods but with the damage suffered with the earthquakes, it was rebuilt. It is thought that this site was also the location of the temple of the Goddess Hera.